Isolation, Characterization and Structural Elucidation of Bioactive Compound in Aurora Globostellata

Isolation, Characterization and Structural Elucidation of Bioactive Compound in Aurora Globostellata

The ocean covers about 70% of the earth surface providing a diverse living environment for invertebrates [1]. Therefore, marine natural products will play a major role in drug discovery in the future. The work on marine natural products started 59 years ago when Bergman discovered the novel bioactive Arabino-nucleoside from marine sponge Cryptotethya crypta [2]. This discovery encouraged natura...

ISOLATION AND STRUCTURAL ELUCIDATION OF THE FIRST KNOWN C-HOMOPROTOBERBERINE

A novel C-homoprotoberberine alkaloid, Hediamine (2), has been isolated from the roots of Berberis actinucantha (Berberidaceae). Conclusive proof for the structure of hediamine was obtained by its comparison with the isomeric lactam (4), by chemical transformation, and by means of spectroscopic techniques (UV, IR, MS, NMR).

Antibacterial activity of crude extracts of Spirulina platensis and its structural elucidation of bioactive compound

The concept of biological control for health maintenance has received widespread attention during the last few years. Therefore, the main objective of this work was to look for active substances that could be used as antibacterial agents. To achieve this target, two different extract (Methanol and Acetone) from Spirulina platensis was examined. The algal extracts were tested in vitro for their ...

isolation and structural elucidation of natural products in euphorbia erythradenia

Isolation and structural elucidation of a new cyclohexenone compound from Lasiodiplodia theobromae.

A new cyclohexenone compound was isolated as a mixture of enantiomers from a culture filtrate of Lasiodiplodia theobromae. The relative structure was determined to be 4,5-dihydroxy-3-methyl-cyclohex-2-enone on the basis of MS, (1)H-NMR, and (13)C-NMR spectroscopic analyses, including 2D-NMR experiments. Resolution of the enantiomers was conducted by a coupling reaction with (S)-MTPA-Cl followed...